Gold-Catalyzed Post-Ugi Ipso-Cyclization with Switchable Diastereoselectivity
نویسندگان
چکیده
منابع مشابه
Post-Ugi gold-catalyzed diastereoselective domino cyclization for the synthesis of diversely substituted spiroindolines
An Ugi four-component reaction of propargylamine with 3-formylindole and various acids and isonitriles produces adducts which are subjected to a cationic gold-catalyzed diastereoselective domino cyclization to furnish diversely substituted spiroindolines. All the reactions run via an exo-dig attack in the hydroarylation step followed by an intramolecular diastereoselective trapping of the immin...
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ژورنال
عنوان ژورنال: The Journal of Organic Chemistry
سال: 2018
ISSN: 0022-3263,1520-6904
DOI: 10.1021/acs.joc.8b00953